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Maternal exercise

SERPINA3C as a mediator of metabolic health in offspring

Nature Metabolism volume 7, pages 245–246 (2025)Cite this article

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Exercise during pregnancy benefits both mother and child. A Nature Metabolism study identifies the adipokine SERPINA3C as crucial for enhancing metabolic health in offspring, and provides insights into the mechanisms behind maternal exercise benefits.

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Fig. 1: Exercise-induced maternal SERPINA3C provides offspring with a metabolically beneficial phenotype.

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Authors and Affiliations

  1. Department of Biomedicine, Aarhus University, Aarhus, Denmark

    Bianca E. Suur & Emma Börgeson

  2. Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark

    Bianca E. Suur & Emma Börgeson

  3. Department of Clinical Immunology and Transfusion Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden

    Emma Börgeson

Authors
  1. Bianca E. Suur
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  2. Emma Börgeson
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Correspondence to Emma Börgeson.

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The authors declare no competing interests.

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Suur, B.E., Börgeson, E. SERPINA3C as a mediator of metabolic health in offspring. Nat Metab 7, 245–246 (2025). https://doi.org/10.1038/s42255-024-01209-2

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