Extended Data Fig. 2: Foods and nutrients in controlled feeding studies.
From: Metagenomic estimation of dietary intake from human stool
(a) Food abundances in the MBD cohort by diet group (n = 30). Boxplots show 25%, 50%, and 75% quantiles.The center denotes the median and whiskers extend to the smallest and largest data points within 1.5 interquartile ranges. (b) Correlation between MEDI estimates and ground truth for varying fecal samples/food diary entry offsets. (c) MEDI predictions of total fiber content from fecal DNA (y-axis) and nutrient consumption of sugars, fibers and grains obtained from food diaries (x-axis) in a controlled-feeding study (PATH), where the dietary intake recorded in the daily food record precede the stool sample by at least 48 h. Each point denotes a single individual. For the food diaries, points represent means over all measured intake amounts and error bars denote the standard error of the mean (sd/sqrt(n)), normalized to a 100 g portion (all samples within the offset, 38 individuals with 124 food record diary entries). For the MEDI data, points x-coordinate represent point estimates of intake based on weighting nutrient profiles of food items by food item relative abundance and assuming a 100 g portion. Blue lines denote regression slopes and gray areas represent 95% confidence intervals. Annotations denote correlation coefficient (r) and p-value (p) from a Pearson product-moment correlation test.
