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Metabolism

Intergenerational metabolic effects of cold exposure

Nature Metabolism volume 7, pages 635–636 (2025)Cite this article

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Parental health during conception and gestation can affect offspring development and health. A study in humans now shows that adult individuals who were conceived during cold seasons exhibit greater brown adipose tissue activity, increased energy expenditure, lower body mass index and lower visceral fat accumulation.

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Fig. 1: Intergenerational effects of parental cold exposure.

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Authors and Affiliations

  1. Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany

    R. Teperino

  2. German Center for Diabetes Research (DZD), Neuherberg, Germany

    R. Teperino

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  1. R. Teperino
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Correspondence to R. Teperino.

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Teperino, R. Intergenerational metabolic effects of cold exposure. Nat Metab 7, 635–636 (2025). https://doi.org/10.1038/s42255-025-01222-z

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