Fig. 4: Metabolic characteristics of 4HPAA- and 3HPP-fed mice.
a, The weekly food intake of HFD-fed mice with or without treatment with 4HPAA, 3HPP or 4HPP for 12 weeks. b–d, The energy expenditure of HFD-fed mice treated with or without 4HPAA (b), 3HPP (c) or 4HPP (d) for 12 weeks (n = 5 mice per group). e, The faecal triglyceride content of HFD-fed mice treated with or without 4HPAA, 3HPP or 4HPP for 12 weeks (n = 6 mice per group). f, Oral glucose tolerance test (OGTT) of HFD-fed mice with or without treatment with 4HPAA, 3HPP or 4HPP for 12 weeks (n = 12 mice for the control group and 6 mice for other groups). g, Insulin tolerance tesr (ITT) of the HFD-fed mice with or without treatment with 4HPAA, 3HPP or 4HPP for 12 weeks (n = 12 mice for the control group and 6 mice for other groups). Data are shown as mean ± s.d. Statistical analysis was performed using the two-tailed Mann–Whitney U test. Experiments were repeated twice independently, with similar results.
