Extended Data Fig. 7: Metabolomics and neuroactive potential analysis.
From: Rapid modulation of gut microbiota composition by hypothalamic circuits in mice
a. Partial Least Squares Discriminant Analysis (PLS-DA) of duodenal metabolomics data showing differential clustering between vehicle- and leptin-treated groups (n = 6 mice per group). b. Bar plot illustrating statistically significant differences in gut-brain modules (GBMs) between leptin- and vehicle-treated groups (n = 8 mice per group). Data are presented as proportional differences, along with corresponding p-values.
