Extended Data Fig. 2: Modulation of AgRP or POMC neuron activity does not induce alterations in gut motility.
From: Rapid modulation of gut microbiota composition by hypothalamic circuits in mice
a. Diagram illustrating the experimental outline for the analysis of gut motility. b–e. Loess curve of intestinal FITC distributions after chemogenetic activation of AgRP (B-C; n = 6 mice per group) and POMC (D-E; n = 7 mice in POMC(-) group and n = 8 mice in POMC(+) group) neurons. X-axis represents different gut segments from stomach to colon. Dot plots represent the geometric mean (g) of FITC proportion. Data are represented as mean ± SEM. Statistical significance was determined using the Wilcoxon test, followed by Benjamini-Hochberg correction. CNO: Clozapine-N-Oxide. FITC: Fluorescein Isothiocyanate.
