Extended Data Fig. 4: Central leptin administration modulates gut motility.
From: Rapid modulation of gut microbiota composition by hypothalamic circuits in mice
a. Diagram illustrating the experimental outline for the analysis of gut motility. b–e. Loess curve of intestinal FITC distributions after intracerebroventricular ghrelin (b, c) and leptin (d, e) administration (n = 7 mice per group). X-axis represents different gut segments from stomach to colon. Dot plots represent the geometric mean (g) of FITC proportion. Data are represented as mean ± SEM. Statistical significance was determined using the Wilcoxon test, followed by Benjamini-Hochberg correction. D, section 1, **p = 0.002; section 2, **p = 0.002; section 11, **p = 0.009. E, **p = 0.0041. FITC: Fluorescein Isothiocyanate.
