Extended Data Fig. 5: Subgroup analysis of primary and key secondary endpoints in the RFITT population at week 2.

a, Resolution of performance drop (primary endpoint). The number of participants indicates those included in the analysis due to the presence of performance drop at baseline. b, Improvement in the ability to perform normal activities (first key secondary endpoint). The number of participants indicates those included in the analysis due to the presence of a sufficiently severe reduction in the ability to perform normal activities (a value of >3 on the 6-point complaint scale) at baseline. c, Improvement in cough (second key secondary endpoint). The number of participants indicates those included in the analysis due to the presence of a sufficiently severe cough (a value of >3 on the 6-point complaint scale) at baseline. d, Resolution of fatigue (third key secondary endpoint). The number of participants indicates those included in the analysis due to the presence of fatigue at baseline. For details regarding symptoms and risk factors, see Supplementary Sections 3.2–3.4. Forest plot graphs represent odds ratios (a, d) or mean deviations (b, c) and the respective lower/upper 95% confidence intervals (CI).