Extended Data Fig. 6: Drug-induced effects on DVC non-neuronal cells. | Nature Metabolism

Extended Data Fig. 6: Drug-induced effects on DVC non-neuronal cells.

From: GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice

Extended Data Fig. 6

UMAP representations of gene expression of DVC non-neuronal cells colored by experimental group (a), cell type (b), or expression of either Glp-1r (c) or Gipr (d). Bar plots with Augur scores of DVC non-neuronal cells from mice treated with either the GIPR antagonist (e), acyl-GLP-1 (f), acyl-GIP (g), or MAR709 (h). Bar plots are ranked and colored by Augur score, representing cell-specific change in gene expression of the respective group relative to vehicle-treated DIO controls.

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