Fig. 5: The nutritional status does not affect food odour-induced activity of MSVGLUT2 neurons.
From: A food-sensitive olfactory circuit drives anticipatory satiety
a–d, Calcium dynamics and AUC of MSVGLUT2 neurons aligned to the onset of the first sniff in response to NCD odours or control exposure (empty bottle), in random fed mice (time curve: paired two-way ANOVA, Sidak post hoc; n = 8 mice; AUC: paired two-tailed Student’s t-test; n = 8 mice; P = 0.054; a), after intraperitoneal (i.p.) saline injection (time curve: paired two-way ANOVA, Sidak post hoc; n = 5 mice; AUC: paired two-tailed Student’s t-test; n = 5 mice; P = 0.0130; b), after i.p. ghrelin injection (time curve: paired two-way ANOVA, Sidak post hoc; n = 5 mice; AUC: paired two-tailed Student’s t-test; n = 5 mice; P = 0.0127; c) and after i.p. GLP-1 injection (time curve: paired two-way ANOVA, Sidak post hoc; n = 5 mice; AUC: paired two-tailed Student’s t-test; n = 5 mice; d). Data are represented as the mean ± s.e.m. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001. Panels a–d created using BioRender.com.
