Extended Data Fig. 3: Differential protein abundance versus acetylation level. | Nature Metabolism

Extended Data Fig. 3: Differential protein abundance versus acetylation level.

From: Lactate signalling leads to aggregation of immune-inflammatory hotspots and SLC5A12 blockade promotes their resolution

Extended Data Fig. 3

Overview of differences in protein abundance as well as acetylation levels between untreated and lactate-treated (12 h a, and 48 h b) CD4 T cells. Proteins with a positive logFC (protein, x-axis) were more abundant in lactate-treated samples, while proteins with a negative logFC were more abundant in untreated samples. For proteins with a positive logFC (acetyl, y-axis), higher acetylation signals were obtained in lactate-treated samples. For proteins with a negative logFC, higher acetylation signals were obtained in untreated samples. (c) Individual array values for a set of differential proteins in untreated and lactate-treated (48 h) CD4 T cells.

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