Extended Data Table 4 Gastrointestinal symptoms during metformin only or in combination with moderate or low FODMAP diets

From: Combining a diet rich in fermentable carbohydrates with metformin improves glycaemic control and reshapes the gut microbiota in people with prediabetes

  1. Symptoms were reported on a visual analogue scale (0-100 mm) with higher scores. Statistical significance was assessed using paired two-sided sample t-tests or Wilcoxon Signed Rank Test to compare M, L, M-M and L-M. Bold values indicate statistically significant. Sample size n= baseline:26, M-M:22 and L-M:22 participants
  2. Abbreviations: GI: gastrointestinal, M: moderate FODMAP diet, L: low FODMAP diet, M-M: moderate FODMAPs with metformin treatment, L-M: low FODMAPs with metformin treatment, BSFS: Bristol Stool Form Scale.