Extended Data Fig. 1: Predictive performance of PISTE using unified-peptide negative sampling and reference-TCR negative sampling methods.

All testing triples whose Antigen-HLA pairs were observed in the training data are removed from the test-sets. (a) The AUROC, AUPR and PPVn for PISTE and competing models using the unified-peptide negative sampling schemes. (b) The AUROC, AUPR and PPVn for PISTE and competing models using the reference-TCR negative sampling schemes. The red baseline represents a random classifier.