Extended Data Fig. 1: Letter shape generation. | Nature Machine Intelligence

Extended Data Fig. 1: Letter shape generation.

From: Efficient protein structure generation with sparse denoising models

Extended Data Fig. 1

(a) Successfully designed letter shapes for letters (S, A, L, D). The designed structure (grey) is overlaid with the best ESMfold prediction (coloured by residue index) out of 10 ProteinMPNN sequences. (b, c) scRMSD, scTM and pLDDT for each backbone (b, n = 10) or designed sequence (c, n = 110, 1 salad sequence and 10 ProteinMPNN sequences per backbone) across all letter designs.

Back to article page