Extended Data Fig. 2: In vitro toxicity assays of CD47-LLO with cancer cell lines. | Nature Cancer

Extended Data Fig. 2: In vitro toxicity assays of CD47-LLO with cancer cell lines.

From: An antibody–toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy

Extended Data Fig. 2

a-h, Flow cytometry analysis and quantification of apoptosis and necrosis in 4T1Br4 (a-b), EO771 (c-d), KPC (e-f), and D4M.3 A (g-h) cells after treatment with 2 μg/mL CD47-LLO for 0, 6, or 24 hours (n = 4 biologically independent experiments for b, d, f, and n = 3 for h). Data shown represent mean ± s.d. (b, d, f, h) analyzed by one-way analysis of variance with Tukey’s multiple comparisons test.

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