Extended Data Fig. 3: Complete blood count and blood biochemistry examination in mice.
From: Engineered bacteria for near-infrared light-inducible expression of cancer therapeutics
CT26 tumor-bearing mice were intratumorally injected with 5 × 106 c.f.u. of ΔXIV. Blood samples were collected on the indicated days post-bacterial injection for a complete blood count and blood biochemistry investigation. (a) Alkaline phosphatase (ALP), (b) aspartate aminotransferase (AST), (c) alanine aminotransferase (ALT), (d) white blood cells, (e) red blood cells, (f) hematocrit, (g) time-course albumin/globin ratios, (h) mean corpuscular hemoglobin, (i) mean corpuscular volume, (j) creatinine (CRE), and (k) blood urea nitrogen (BUN) from healthy mice (control) and bacteria-treated mice were detected. Data are presented as means ± s.e.m.; n = 4 mice per group. Statistical analyses were performed using a one-way ANOVA followed by Tukey’s test with multiple comparisons.
