Extended Data Fig. 4: Schematic depicting the genetic arrangement of the plasmid.
From: Engineered bacteria for near-infrared light-inducible expression of cancer therapeutics
a, Plasmid layouts of the NETMAP system inducing the expression of PD-L1nb and CTLA-4nb, respectively. b, Schematic depicting the genetic arrangement of the plasmid for ΔXIVPadC4 construction employing the Tn7 transposon system. The coding sequences of PadC4 and BphO, along with their constitutive promoter Ptac, were placed into the genome of ΔXIV using the Tn7 transposon, forming ΔXIVPadC4. c, Schematic diagram of the experimental procedure for developing a stable ΔXIVPadC4 strain.
