Extended Data Fig. 1: Molecular profiling of paired tissue and plasma comparison at baseline in the validation cohort.
a, Concordance analysis of primary tumor and plasma baseline somatic SNVs. The cohort’s median concordance is represented by a dot. b, Comparative molecular landscape of pathogenic mutations and CNV in paired tissue and plasma samples at baseline from 15 colorectal cancer CC patients. Each box illustrates a mutated gene in a specific patient, divided into two sections: the left section displays results from the primary tissue, and the right section depicts plasma at baseline. Similarly, each box at a given collection moment is subdivided into two parts, with the left indicating point mutations, and the right representing CNVs. The Y-axis is arranged by the number of point mutations for each gene across all patients.
