Extended Data Fig. 2: Molecular landscape of the paired tissue-plasma comparison at relapse.

Comparative analysis of the molecular landscape, focusing on pathogenic mutations and CNVs, in paired tissue and plasma samples collected at the point of relapse from 17 CC patients. Each box within the representation signifies a mutated gene in an individual patient, and it is divided into two sections by a line. The left part corresponds to outcomes derived from the metastatic tissue, while the right part corresponds to plasma at the time of relapse. Similarly, each box corresponding to a collection moment is further divided into two components, with the left indicating point mutations, and the right representing CNVs. The Y-axis is arranged based on the number of point mutations for each gene across all patients.