Extended Data Fig. 5: Additional findings in BRAF-mutant glioma in ages 0-40. | Nature Cancer

Extended Data Fig. 5: Additional findings in BRAF-mutant glioma in ages 0-40.

From: A population-based analysis of the molecular landscape of glioma in adolescents and young adults reveals insights into gliomagenesis

Extended Data Fig. 5

(A) OS of HGG with different driver mutations (n = 97 patients). P-value calculated using Log-rank test. (B) PFS and OS of BRAF-mutant tumors in AYA Toronto cohort stratified by histology (n = 71 patients). P-value calculated using Log-rank test. (C) PFS of BRAF mutant LGG in AYA based on extent of resection (n = 57 patients). P-value calculated using Log-rank test. (D) PFS of BRAF mutant LGG based on location (n = 57 patients). P-value calculated using Log-rank test. (E) Multivariate analysis of factors influencing PFS in BRAF p.V600E mutant LGG. P-value calculated using Cox regression, error bars show 95% confidence intervals. (F) Multivariate analysis of factors influencing OS in BRAF p.V600E mutant HGG. P-value calculated using Cox regression, error bars show 95% confidence intervals.

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