Extended Data Fig. 4: Volcano plots of hepatic DEGs after Low Ile feeding in aged mice.
From: Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging
(A-B) Volcano plots of differentially expressed genes in the liver of (blue) male and (red) female mice with (A) age and (B) diet. DEGs were identified using an empirical Bayes moderated linear model, and log coefficients and Benjamini-Hochberg (BH) adjusted p-values were generated for each comparison of interest (α = 0.10).
