Table 4 Mean and standard deviation of ECG intervals and amplitudes across leads

ECG feature	Lead	Real data	1-lead reconstruction	p(means)	p(variance)	2-lead reconstruction	p(means)	p(variance)
RR interval (ms)		886 ± 161	887 ± 164	0.08	1.0	887 ± 162	1.0	0.4
QT interval (ms)		397 ± 30	399 ± 31	2E−16	1.0	400 ± 30	2E−13	2E−13
PR interval (ms)		160 ± 23	160 ± 20	0.3	0.001	159 ± 22	0.6	0.0001
QRS duration (ms)		91 ± 9	90 ± 7	0.06	2E−16	91 ± 7	2E−12	0.2
R amplitude (μV)	V1	161 ± 124	135 ± 51	2E−12	2E−16	126 ± 61	2E−16	2E−16
	V2	504 ± 306	329 ± 87	2E−16	2E−16	401 ± 111	2E−16	2E−16
	V3	856 ± 477	726 ± 132	2E−16	2E−16	784 ± 179	3E−6	2E−16
	V6	1073 ± 325	1106 ± 192	0.001	2E−16	1038 ± 256	7E−6	2E−13
T amplitude (μV)	V1	−2 ± 121	0 ± 61	0.6	2E−16	26 ± 63	6E−14	2E−16
	V2	419 ± 233	378 ± 112	7E−9	2E−16	466 ± 117	2E−11	2E−16
	V3	481 ± 227	430 ± 123	4E−14	2E−16	514 ± 137	2E−7	2E−16
	V6	236 ± 98	245 ± 76	0.0004	5E−14	242 ± 95	0.0008	0.4
S amplitude (μV)	V1	820 ± 365	800 ± 164	0.08	2E−16	799 ± 215	0.04	2E−16
	V2	1173 ± 491	1020 ± 154	2E−16	2E−16	1045 ± 213	2E−16	2E−16
	V3	894 ± 427	703 ± 123	2E−16	2E−16	794 ± 182	2E−13	2E−16
	V6	53 ± 79	23 ± 36	2E−16	2E−16	56 ± 71	0.03	0.001
ST amplitude (μV)	V1	34 ± 29	29 ± 17	1E−7	2E−16	40 ± 24	9E−7	2E−10
	V2	91 ± 66	70 ± 34	2E−16	2E−16	85 ± 39	0.0005	2E−16
	V3	73 ± 66	72 ± 36	0.3	2E−16	75 ± 46	0.4	2E−16
	V6	7 ± 27	9 ± 19	0.005	2E−16	12 ± 28	5E−9	0.1

Mean and standard deviation for RR, QT, PR intervals, QRS duration, and R, T, S peak amplitudes, and ST amplitudes of real and generated reconstructed data in leads V1, V2, V3, and V6. The results were derived from the GAN models trained using both 1-lead and 2-lead configurations. Real data vs. reconstructed data where tested for differences in mean using a t-test, and variance tested using an F-test.

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