Fig. 6: hCiCMs provides cardioprotection in swine with ischemic heart injury. | Communications Medicine

Fig. 6: hCiCMs provides cardioprotection in swine with ischemic heart injury.

From: Reprogramming of human urine cells into cardiomyocytes via a small molecule cocktail in xeno-free conditions

Fig. 6

a Schematic showing the swine study design. b Angiography of swine during myocardial infarction surgery through chemical glue occlusion procedure. c Representative ECG during MI surgery. d Representative M-mode images of echocardiography measurement of cardiac function. e Evaluation of cardiac functions with echocardiography. Ejection fraction (EF), left ventricular fractional shortening (LVFS), left ventricular posterior wall in diastole (LVPWd), left ventricular posterior wall in systole (LVPWs), Interventricular septum in diastole (IVSd), and interventricular septum in systole (IVSs) were presented of swine treated with hCiCMs or vehicle (n = 4, exact p values are provided in a file named Supplementary Data 5). f Images of Masson trichrome staining of the heart sections from the MI swine treated with hCiCMs or vehicle (n = 4), Scale bar =5 mm. g Quantitative analysis of infarct size of h. Statistical analysis was performed by two-tailed unpaired t test. Exact p values are provided in a file named Supplementary Data 5.

Back to article page