Fig. 4: Extrapolative tests of MT-GNN.

a, Experimental test data and prediction accuracy by MT-GNN, RF and single-task GNN. b, Visualization of the encoding space of MT-GNN, RF and single-task GNN using PCA. c, Quantitative distance between data points along the principal component. d, An additional extrapolative test containing N-substituted indoles as substrates by the MT-GNN model.