Extended Data Fig. 5: Genes mapped from epistatic loci share transcription factors and splicing regulators.
From: Epistasis regulates genetic control of cardiac hypertrophy
Gene pairs exhibiting strong co-association with transcription factors (TFs) and RNA-binding regulators (p < 0.05, two-sided Fisher’s exact test, Fig. 4e) are displayed. Horizontal bars indicate the number of shared TFs or RNA-binding regulators (bottom axis), with the top-ranked TF or regulator, determined by the lowest two-sided enrichment p-value (dots, top axis), labeled on each bar. Bars are color-coded by the corresponding gene set library. Detailed information can be found in Supplementary Data 7.
