Table 4 Results of Naive and Conservative Testing

From: Development of the treatment prediction model in the artificial intelligence in depression – medication enhancement study

Test

Sample N on which test was conducted

Baseline remission rate before model

Remission rate as per the test

Absolute difference

Relative difference (Absolute difference / baseline)

Average difference (%) between best and worst drug for each patient

Naive

875

43.63

53.98

10.35

0.24

10.8

Conservative- predicted remission

8167i

43.21*

57.41*

14.2*

0.33*

n/a**

Conservative- actual remission

8167i

43.21*

55.08*

11.87*

0.28*

n/a**

  1. *Rates are based on the average of the samples taken for our bootstrap (n = 100) analysis.
  2. **Analysis not carried out given the large number of folds.
  3. iBootstrap analysis was carried out on the combined train and validation sets.
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