Insect-derived proteins and fats present viable food constituents. They can be bioengineered and fermented to improve their nutritional value and functionality to promote food security and the development of new superfoods. Nonetheless, scale-up production and translation of insect-derived proteins and fats remain difficult.
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References
Gharibzahedi, S. M. T. & Altintas, Z. Integrated ultrasonic-transglutaminase modification of lesser mealworm protein isolate: A pioneering cobalamin delivery vehicle in gluten-free breads. Food Chem. 448, 139069 (2024).
Gharibzahedi, S. M. T. & Altintas, Z. Ultrasound-assisted alcoholic extraction of lesser mealworm larvae oil: Process optimization, physicochemical characteristics, and energy consumption. Antioxidants 11, 1943 (2022).
Lange, K. W. & Nakamura, Y. Edible insects as future food: chances and challenges. J. Future Foods 1, 38–46 (2021).
Gharibzahedi, S. M. T. & Altintas, Z. Lesser mealworm (Alphitobius diaperinus L.) larvae oils extracted by pure and binary mixed organic solvents: Physicochemical and antioxidant properties, fatty acid composition, and lipid quality indices. Food Chem. 408, 135209 (2023).
Gharibzahedi, S. M. T. & Altintas, Z. Transglutaminase-crosslinked lesser mealworm protein isolate: A new milk fat substitute for high-quality probiotic set yogurts. Food Hydrocoll. 146, 109172 (2024).
Dridi, C., Millette, M., Aguilar, B., Salmieri, S. & Lacroix, M. Storage stability of a fermented probiotic beverage enriched with cricket protein hydrolysates. Food Bioprocess Technol. 15, 2587–2600 (2022).
Miserez, A., Yu, J. & Mohammadi, P. Protein-based biological materials: molecular design and artificial production. Chem. Rev. 123, 2049–2111 (2023).
Tuncel, A. et al. Genome-edited foods. Nat. Rev. Bioeng. 1, 799–816 (2023).
Choi, K. R. & Lee, S. Y. Systems metabolic engineering of microorganisms for food and cosmetics production. Nat. Rev. Bioeng. 1, 832–857 (2023).
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The authors acknowledge support of the Alexander von Humboldt Foundation via the Georg Forster Research Fellowship.
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S.M.T.G and Z.A. discussed and prepared the article and approved the final version of the text.
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Gharibzahedi, S.M.T., Altintas, Z. Bioengineered insect proteins and fats as high-quality and sustainable food constituents. Nat Rev Bioeng 2, 804–805 (2024). https://doi.org/10.1038/s44222-024-00221-1
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DOI: https://doi.org/10.1038/s44222-024-00221-1