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Improving transfusion medicine in resource-limited settings by point-of-care diagnostics

Nature Reviews Bioengineering volume 3, pages 718–720 (2025)Cite this article

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To ensure comprehensive understanding of blood group antigens — including minor antigens — blood transfusions require extended erythrocyte phenotyping or genotyping. However, such advanced testing is frequently unavailable in resource-limited settings. Implementing point-of-care testing on extended blood group antigens can enhance patient care in transfusion medicine by improving the accessibility, safety and efficiency of blood transfusions.

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Fig. 1: Point-of-care-based diagnostics in transfusion medicine.

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Acknowledgements

R.R. and P. Mohanty acknowledge the Indian Institute of Science Education and Research Berhampur for their fellowship. P. Moitra acknowledges the Indian Institute of Science Education and Research Berhampur for funding.

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Authors and Affiliations

  1. Department of Chemical Sciences, Indian Institute of Science Education and Research Berhampur, Ganjam, India

    Rijo Rajeev, Paresh Mohanty & Parikshit Moitra

  2. Department of Transfusion Medicine, Tata Medical Center, Kolkata, India

    Suvro Sankha Datta

Authors
  1. Rijo Rajeev
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  2. Paresh Mohanty
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  3. Suvro Sankha Datta
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  4. Parikshit Moitra
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Contributions

S.S.D. and P. Moitra conceived the idea. R.R. and P. Mohanty drafted the initial version and revised the manuscript in consultation with and per the suggestions of S.S.D. and P. Moitra. All authors agreed to the final version of the submitted manuscript.

Corresponding authors

Correspondence to Suvro Sankha Datta or Parikshit Moitra.

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The authors declare no competing interests.

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Rajeev, R., Mohanty, P., Datta, S.S. et al. Improving transfusion medicine in resource-limited settings by point-of-care diagnostics. Nat Rev Bioeng 3, 718–720 (2025). https://doi.org/10.1038/s44222-025-00331-4

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