Table 2 Characteristics of bacterial isolates
From: Epidemiological Genomics of Klebsiella pneumoniae isolates from hospitals across Colombia
No. isolates (% of total) | CGs and STs mainly associated | p-value | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Carbapenemases | CG258 | CG1082 | CG307 | CG147 | CG12 | |||||
ST11 | ST258 | Others | ST1082 | ST307 | ST147 | Others | ST12 | |||
blaKPC-2 | 60 (17.9) | -- | 5 | -- | -- | 3 | 2 | 4 | 7 | <0.001 |
blaKPC-3 | 80 (23.9) | 41 | 6 | 3 | 13 | 3 | -- | -- | -- | <0.001 |
blaKPC-19 | 1 (0.3) | -- | -- | -- | -- | -- | -- | -- | -- | 0.5 |
blaNDM-1 | 18 (5.4) | -- | -- | -- | -- | 4 | 4 | -- | -- | <0.001 |
blaVIM-24 | 2 (0.6) | 1 | -- | -- | -- | -- | -- | -- | -- | 0.7 |
blaGES-2 | 1 (0.3) | -- | -- | -- | -- | -- | -- | -- | -- | 0.4 |
Coproductions | CG147 | CG268 | CG37 | CG11551 | CG294 | CG17/20 | CG10881 | CG258 | ||
ST147 | ST433 | ST37 | ST5994 | ST6696 | ST17 | ST4343 | ST11 | |||
blaGES-2+blaKPC-2 | 1 (0.3) | -- | -- | -- | -- | -- | 2 | -- | -- | 0.3 |
blaKPC-2+blaNDM-1 | 6 (1.8) | 2 | 1 | 1 | 1 | 1 | -- | -- | -- | 0.018 |
blaKPC-2+blaNDM-1+blaVIM-24 | 1 (0.3) | -- | -- | -- | -- | -- | -- | 1 | -- | 0.093 |
blaKPC-3+blaVIM-24 | 1 (0.3) | -- | -- | -- | -- | -- | -- | -- | 1 | >0.9 |
ESβL | CG258 | CG307 | CG147 | CG1082 | CG14 | |||||
ST11 | ST258 | ST307 | ST147 | ST392 | ST6693 | ST1082 | ST14 | |||
ESBL + carbapenemases | 83 (24.8) | 37 | 1 | 10 | 4 | 3 | 1 | 6 | 4 | -- |
ESBL, but no carbapenemases | 42 (12.5) | 5 | -- | 4 | 2 | -- | -- | 2 | 2 | -- |
No carbapenemases/ESBL | 141 (42.1) | 1 | -- | -- | -- | -- | -- | -- | -- | -- |
K-locus | CG258 | CG380 | CG14 | CG307 | CG268 | |||||
ST11 | ST380 | ST6697 | ST679 | ST14 | ST307 | ST433 | ST36 | |||
KL105 | 45 (13.4) | 44 | -- | -- | 1 | -- | -- | -- | -- | <0.001 |
KL2 | 33 (9.9) | -- | 10 | 3 | -- | 6 | -- | -- | -- | <0.001 |
KL102 | 22 (6.6) | -- | -- | -- | -- | -- | 14 | 3 | 2 | <0.001 |
Others | 235 (70.1) | 3 | -- | -- | -- | 2 | -- | -- | -- | -- |
O-Locus | CG258 | CG1082 | CG307 | CG111 | CG380 | CG14 | ||||
ST11 | ST258 | ST1082 | ST307 | ST11 | ST567 | ST380 | ST14 | |||
O1/O2v2 | 171 (51) | 44 | 6 | 15 | 14 | 7 | 2 | -- | -- | <0.001 |
O1/O2v1 | 72 (21.5) | 3 | -- | -- | -- | -- | -- | 10 | 14 | <0.001 |
Others | 92 (27.5) | -- | 4 | -- | -- | -- | -- | -- | -- | -- |
Virulence genes | CG258 | CG23 | CG380 | CG3583 | -- | |||||
ST11 | ST258 | 6694 | ST23 | ST380 | ST6697 | ST2039 | -- | |||
Yersiniabactin (ybt) | 108 (32.2) | 43 | 9 | 1 | 7 | 10 | 3 | 2 | -- | <0.001 |
Colibactin (clb) | 15 (4.5) | -- | 4 | 1 | 7 | -- | -- | 2 | -- | 0.029 |
Salmochelin (iro) | 16 (4.8) | -- | -- | -- | 7 | truncated | 2 | 2 | -- | 0.2 |
Aerobactin (iuc) | 25 (7.5) | -- | -- | -- | 6 | 7 | 1 | 2 | -- | 0.2 |
RmpADC (rmp) | 31 (9.3) | -- | -- | -- | 7 | 9 | 2 | 2 | -- | 0.09 |
rmpA2 | 13 (3.9) | -- | -- | -- | 7 | -- | -- | -- | -- | 0.028 |
