Table 1 Demographics of male and female patients with gastric adenocarcinoma (GAC).

From: Sex disparity in survival outcomes of advanced gastric adenocarcinoma

 

F (n = 202)

M (n = 224)

Total (N = 426)

p value

Age

   

0.19

 - Median

64.0

66.0

65.0

 

 - Mean

62.2

64.0

63.2

 

 - Range

21.0–93.0

27.0–91.0

21.0–93.0

 

 - SD

15.61

13.24

14.42

 

Ethnicity

   

0.29

 - Asian

56 (27.7%)

66 (29.5%)

122 (28.6%)

 

 - Black

19 (9.4%)

16 (7.1%)

35 (8.2%)

 

 - Hispanic

26 (12.9%)

29 (12.9%)

55 (12.9%)

 

 - Other

44 (21.8%)

34 (15.2%)

78 (18.3%)

 

 - White

57 (28.2%)

79 (35.3%)

136 (31.9%)

 

PS

   

0.77

 - ECOG 0–1

104 (51.5%)

108 (48.2%)

212 (49.8%)

 

 - ECOG 2–4

37 (18.3%)

42 (18.8%)

79 (18.5%)

 

 - Unknown

61 (30.2%)

74 (33.0%)

135 (31.7%)

 

CCI

   

0.01

 - Median

1.00

1.00

1.00

 

 - Mean

1.15

1.57

1.37

 

 - Range

0.0–10.0

0.0–7.0

0.0–10.0

 

 - SD

1.62

1.87

1.77

 

Histology Type

   

0.02

 -Diffuse

42 (20.8%)

23 (10.3%)

65 (15.3%)

 

 -Intestinal

7 (13.4%)

38 (17.0%)

65 (15.3%)

 

 -Mixed

6 (3.0%)

6 (2.7%)

12 (2.8%)

 

 -Unknown

127 (62.9%)

157 (70.1%)

284 (66.7%)

 

Chemotherapy

   

0.45

 - N

41 (20.3%)

39 (17.4%)

80 (18.8%)

 

 - Y

161 (79.7%)

185 (82.6%)

346 (81.2%)

 

Receipt of ICI

   

0.40

 - N

103 (51.0%)

105 (46.9%)

208 (48.8%)

 

 - Y

99 (49.0%)

119 (53.1%)

218 (51.2%)

 

HER2

   

0.35

 - neg

186 (92.1%)

202 (90.2%)

388 (91.1%)

 

 - pos

16 (7.9%)

22 (9.8%)

38 (8.9%)

 

TP53

   

0.35

 - wt

92 (45.5%)

92 (41.1%)

184 (43.2%)

 

 - mut

110 (54.5%)

132 (58.9%)

242 (56.8%)

 

Mutp53

   

0.48

 - Non-GOF

83 (41.1%)

105 (46.9%)

188 (44.1%)

 

 - GOF

27 (13.4%)

27 (12.1%)

54 (12.7%)

 

KRAS

   

0.68

 - wt

175 (86.6%)

197 (87.9%)

372 (87.3%)

 

 - mut

27 (13.4%)

27 (12.1%)

54 (12.7%)

 

CDKN2A

   

0.18

 - wt

169 (83.7%)

176 (78.6%)

345 (81.0%)

 

 - mut

33 (16.3%)

48 (21.4%)

81 (19.0%)

 

PIK3CA

   

0.51

 - wt

180 (89.1%)

195 (87.1%)

375 (88.0%)

 

 - mut

22 (10.9%)

29 (12.9%)

51 (12.0%)

 

MYC

   

0.97

 - negative

191 (94.6%)

212 (94.6%)

403 (94.6%)

 

 - positive

11 (5.4%)

12 (5.4%)

23 (5.4%)

 
  1. CCI Charlson comorbidity index, ICI immune checkpoint inhibitor, Wt wild-type, Mut mutant, Mutp53 p53 mutation, GOF gain-of-function, Non-GOF non-gain-of-funciton.