Fig. 1: Comparison of risk factors, decidual defects and current understanding of aetiology of PAS and pre-eclampsia.
From: Biological comparisons between pre-eclampsia and placenta accreta spectrum

PAS is a uterine disorder secondary to iatrogenic uterine injury, which results in a defective or absent decidua, and deep myometrial EVT invasion. In pre-eclampsia, decidual resistance results in shallow trophoblast invasion, and subsequent systemic maternal and foetal complications. PAS Placenta Accreta Spectrum. EVT Extravillous Trophoblast.