Fig. 2: Volcano plots of metabolites of women with normal pregnancies and threatened miscarriages. | npj Women's Health

Fig. 2: Volcano plots of metabolites of women with normal pregnancies and threatened miscarriages.

From: Untargeted metabolomics reveals key pathways in miscarriage: steroid, folate, fatty acid & glycosaminoglycan metabolism

Fig. 2

a Volcano plot for metabolites in patients with threatened miscarriage (TM) vs those with normal pregnancies (NP). Metabolites which were significantly different (Fold Change (FC) ≥ 2 or ≤0.5, and raw p-value < 0.05) are highlighted. FC is expressed with NP as reference. b Volcano plot for metabolites in patients with threatened miscarriage who eventually miscarried (TMMC) vs those who had ongoing pregnancies (TMO). Metabolites which were significantly different (Fold Change (FC) ≥ 2 or ≤0.5, and raw p-value < 0.05) are highlighted. (FC is expressed with NP as reference). Red hues indicate metabolites with increased abundance in the TM group compared to NP (positive fold change), while blue hues indicate metabolites with decreased abundance in the TM group compared to NP (negative fold change). Black/gray points represent metabolites that do not meet the statistical significance threshold.

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