Fig. 10: Variability in sickness behavior observed in JUAV-infected adult mice. | npj Viruses

Fig. 10: Variability in sickness behavior observed in JUAV-infected adult mice.

From: Juruaça virus taxonomy, tolerance and resistance to infection, and inflammatory response modulation in murine model

Fig. 10

Panels showing variability in sickness behavior in JUAV-infected adult mice: A and E Mice from Group 1 (G1) exhibiting no clinical signs. B and F An infected mouse from Group 2 (G2) showing moderate clinical signs, including ruffled fur, hunched posture, and hindlimb clasping. C and D Mice from Group 3 (G3) displaying severe clinical signs such as hindlimb paralysis, significant weight loss (C), and pronounced hunched posture (D). G Comparison of brain mass between a control uninfected brain (left, n = 13) and an infected brain from a G2 mouse (right), showing severe brain mass loss. Both G2 and G3 animals exhibited similar brain shrinkage (n = 36). Clinical observations were replicated in two independent experiments.

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