Fig. 11: Viral antigen immunolabeling and hematoxylin counterstaining of brain tissue in JUAV-infected mice. | npj Viruses

Fig. 11: Viral antigen immunolabeling and hematoxylin counterstaining of brain tissue in JUAV-infected mice.

From: Juruaça virus taxonomy, tolerance and resistance to infection, and inflammatory response modulation in murine model

Fig. 11

Photomicrographs of brain tissue sections from control (n = 5, A–C) and JUAV-infected (n = 15, D–L) mice, immunolabeled for viral antigens and counterstained with hematoxylin. A–C Control mice showing no viral antigen immunolabeling in the cerebral cortex (A), cerebellum (B), or spinal cord (C). D–F Infected Group 1 (G1) mice showing no viral antigen immunolabeling in the cerebral cortex (D), cerebellum (E), or spinal cord (F). G–I Infected Group 2 (G2) mice showing conspicuous viral antigen immunolabeling (arrows) in the cerebral cortex (G), cerebellum (H), and spinal cord (I). J–L Infected Group 3 (G3) mice showing conspicuous viral antigen immunolabeling (arrows) in the cerebral cortex (J), cerebellum (K), and spinal cord (L). Scale bar = 50 µm. Immunolabeling data were consistent across three independent experiments.

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