Table 1 Studies of ultrasound localization microscopy of the kidney and their measurement conditions. Human studies are marked in green.

From: Advanced ultrasound methods to improve chronic kidney disease diagnosis

Paper first author

Year

Subject(s)

Frame-rate in Hz

US-System

Transducer

Contrast agent

Motion correction

Remarks

Huang56

2021

human

250

Mindray Resona 7

Mindray

L9-3U

SonoVue bolus, acquisition time < 10 s

Rigid

 

Bodard57

2023

human

14–64

Canon Aplio i800

Canon

i8cX1

SonoVue bolus injection, 1-3 min acquisition

none

Allograft kidneys

Denis57

2023

rat

400

Vantage 256

Verasonics

L22-14

Sonovue

Infusion/acquisition for 3 min

none

Kidney externalized and fixed with pins on plastic plate

Qiu49

2022

rat

400

Vantage 256

Vermon

L15 Xtech

Sonovue, bolus injection, acquisition after 20 s for 15 s

Rigid

Non-invasive imaging

Zhang50

2023

Taghavi53

2021

rat

54

BK 5000 modified clinical system

BK

X18L5s

SonoVue 10 min infusion

Non-rigid, respiratory gating,

surgically exposed kidney with fixation by metal retractor

Taghavi59

2022

Søgaard51

2022

Andersen12

2020

Andersen60

2021

Andersen52

2022

Foiret48

2017

Rat

300

Vantage 256

Philips

CL15-7

Self-produced lipid microbubbles

Rigid, Respiratory gating

 

Chen61

2020

mouse

250

Vantage 128

Verasonics L22-14

Definity bolus injection acquisition after 10 s for 4 s

Rigid

No tracking, only localization

Lei54

2022

macaque

500

Vantage 256

Jiarui Electronics Company

L9-4

Sonovue bolus injection, 3 s acquisition time

2-stage affine and non-rigid

 

Song55

2018

rabbit

500

Vantage

Verasonics

L11-3v

Optison, bolus injection acquisition time 2 s

Rigid