Fig. 3: Benchmarking CellMincer and two other denoising methods on paired optical and patch clamp datasets.
From: Robust self-supervised denoising of voltage imaging data using CellMincer
a Sample denoised ROI-averaged neuron traces (color), aligned to the EP-derived ground truth (black). b Inlays of subthreshold activity as indicated in the previous column, magnified. c Distributions of lagged cross-correlations between denoised single-neuron traces and their corresponding aligned EP signals. Their medians are overlaid with peak correlations at Δt = 0 labeled. d Average noise reductions at varying frequency ranges achieved through denoising. e Peak-calling accuracy F1-scores over a range of EP peak prominence levels, using the EP signal as ground truth. Abbreviations: ROI (region of interest).
