Fig. 3: In vivo 2D FID-CSI data obtained from 2 injections of an exemplary mouse with HP PA at 38.2 °C and 34.5 °C rectal body temperatures. | npj Imaging

Fig. 3: In vivo 2D FID-CSI data obtained from 2 injections of an exemplary mouse with HP PA at 38.2 °C and 34.5 °C rectal body temperatures.

From: Temperature dependent chemical shifts of pyruvate and lactate enable in vivo hyperpolarized 13C MRSI thermometry

Fig. 3

T2w anatomical reference image (a) and both pyruvate (b) and lactate (c) peak area integral maps from the CSI at a decreased rectal temperature. d 2x-interpolated apparent temperature map (average temperature: 36.1 ± 1.8 °C, native resolution shown as white square) calculated from CSI data for the injection at a decreased rectal temperature. e Elevated rectal temperature map (average temperature: 40.0 ± 1.7 °C, kidney ROI shown as white dotted line). f Exemplary spectrum (black) and fit of a kidney voxel (red: 38.2 °C, blue: 34.5 °C, white squares in d/e) for both elevated and decreased rectal temperature injections, with pyruvate and lactate peak areas as insets. g Histogram of apparent temperatures for both datasets shown in (d, e).

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