Fig. 1: Schematic representation of the pathophysiologic changes observed in AS, highlighting the histological transitions observed within each layer of the arterial wall as AS progresses. | npj Cardiovascular Health

Fig. 1: Schematic representation of the pathophysiologic changes observed in AS, highlighting the histological transitions observed within each layer of the arterial wall as AS progresses.

From: Impact of cardiometabolic risk factors and its management on the reversion and progression of arterial stiffness

Fig. 1

Changes observed in each layer can occur regardless of the underlying etiology of arterial stiffness. Created in BioRender. Bello Chavolla, O. (2025) https://BioRender.com/o88u142. ECM extracellular matrix RAAS renin-angiotensin-aldosterone system VSMC vascular smooth cells AS arterial stiffness.

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