Table 2 Participant characteristics according to sex-pooled IGFBP7 tertiles

From: The senescence-inducing factor IGFBP7 and risk of atrial fibrillation: findings from the PREVEND study

Characteristics

Tertile 1

Tertile 2

Tertile 3

P value

 

n = 1962

n = 1961

n = 1961

 

IGFBP7 (median, P25–P75), µg/L

70.8 (64.5–77.1)

84.7 (79.5–88.9)

101.2 (95.7–110.1)

<0.001

Age (mean, SD), years

47.1 (9.4)

52.4 (10.6)

61.2 (11.6)

<0.001

Female sex, n (%)

1011 (51.5)

1010 (51.5)

10101 (51.5)

1.00

Height (mean, SD), cm

173.2 (9.5)

173.0 (9.5)

171.7 (9.5)

<0.001

Weight (mean, SD), kg

78.6 (13.9)

79.4 (14.3)

80.4 (14.7)

<0.001

Relative fat mass, %

31.1 (6.9)

31.8 (7.2)

33.2 (7.5)

<0.001

Body mass index, kg/m2

26.2 (4.0)

26.5 (4.2)

27.3 (4.6)

<0.001

SBP (mean, SD), mm Hg

120.6 (14.7)

124.4 (18.0)

132.9 (21.1)

<0.001

Antihypertensive medication, n (%)

236 (12.1)

367 (18.7)

694 (35.4)

<0.001

Smoking

   

<0.001

 Current, n (%)

626 (31.9)

549 (28.0)

427 (21.8)

 

 Past, n (%)

733 (37.4)

814 (41.5)

941 (48.0)

 

Diabetes, n (%)

74 (3.8)

101 (5.2)

206 (10.6)

<0.001

MI or stroke, n (%)

87 (4.4)

129 (6.6)

213 (10.9)

<0.001

Heart failure, n (%)

5 (0.3)

11 (0.6)

34 (1.7)

<0.001

NT-proBNP (median, P25–P75), ng/L

35.0 (18.0–61.0)

38.0 (21.0–70.0)

60.0 (30.0–119.0)

<0.001

UAE (median, P25–P75), mg/24 h

7.6 (5.8–11.1)

8.0 (5.9–12.4)

9.7 (6.3–20.2)

<0.001

eGFR (mean, SD), mL/min/1.73 m2

101.3 (12.5)

94.5 (13.2)

80.6 (16.7)

<0.001

  1. Continuous variables are presented as mean (standard deviation) or as a median (percentile 25 to percentile 75), and categorical variables as n (%).
  2. AF atrial fibrillation, IGFBP7 insulin-like growth factor binding protein-7, SBP systolic blood pressure, NT-proBNP N-terminal pro-B-type natriuretic peptide, UAE 24-h urinary albumin excretion, eGFR estimated glomerular filtration rate.
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