Table 2 Univariate and Multivariate Analyses of Independent Factors Associated with Steatosis

From: Association of metabolic abnormalities and the risk of hepatic fibrosis

 

Univariate

Multivariate

 

OR

p

OR

p

Age

1.01 (1.00–1.02)

0.003

1.00 (0.99–1.01)

0.403

Sex

1.44 (1.14–1.81)

0.002

2.45 (1.76–3.41)

< 0.001

Race

 Black

Reference

   

 Hispanic

2.14 (1.56–2.94)

< 0.001

1.98 (1.36–2.87)

< 0.001

 White

1.70 (1.27–2.28)

< 0.001

1.65 (1.17–2.34)

0.004

 Waist circumference ≥ 102 cm in males and ≥ 88 cm in females

6.69 (5.00–8.96)

< 0.001

3.81 (2.74–5.30)

< 0.001

 Hypertension

2.20 (1.69–2.86)

< 0.001

1.68 (1.25–2.25)

< 0.001

 Triglyceride ≥ 150 mg/dL

2.30 (1.69–3.13)

< 0.001

1.41 (0.99–2.01)

0.058

 HDL-C < 40 mg/dL in males and <50 mg/dL in females

1.54 (1.03–2.31)

0.037

0.56 (0.34–0.92)

0.021

 Prediabetes

2.43 (1.85–3.18)

< 0.001

  

 HOMA-IR ≥ 2.5

4.62 (3.60–5.92)

< 0.001

2.26 (1.70–3.01)

< 0.001

 hsCRP > 2 mg/L

2.76 (2.16–3.52)

< 0.001

1.73 (1.30–2.29)

< 0.001

 Platelet × 100, 109/L

1.57 (1.29–1.90)

< 0.001

1.31 (1.05–1.62)

0.017

 AST/ALT

0.19 (0.13–0.28)

< 0.001

0.44 (0.29–0.67)

< 0.001

  1. HDL-C high-density lipoprotein cholesterol, HOMA-IR homeostatic model assessment of insulin resistance, hsCRP high-sensitive C-reactive protein, ALT alanine transaminase, AST aspartate transaminase.
  2. Prediabetes is defined as fasting plasma glucose = 100–125 mg/dL or HbA1c = 5.7%–6.4%.
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