Fig. 3: Population differences in hemodynamic responses during the Verbal Fluency task.
From: A functional neuroimaging biomarker of mild cognitive impairment using TD-fNIRS
a Shown are t-statistics from independent t-tests between HC with MCI applied to each region of the GLM-based activation maps. Each row corresponds to a different task condition (top: control, middle: semantic, bottom: phonological) and the two columns represent HbO/HbR respectively. Warmer colors are indicative of more activation (or less deactivation) in the HC cohort while cooler colors are indicative of more activation (or less deactivation) in the MCI cohort. b Distributions of GLM test statistics for representative modules shown for the HC (blue) and MCI (red) cohorts for each condition (corresponding row). Solid colored lines indicate the mean for HC (blue) and MCI (red). T-statistics and uncorrected p-value for the independent T-test (HC vs MCI), as well as Cohen’s d are displayed above each plot. For the location of each module number, see Supplement S3, or match symbols displayed next to the x-label to the topo plot from (a) in the same row.
