Figure 3
(a–b) Numbers of ruptured (red), thin-cap (green), mid-cap (black), thick-cap (purple) and total atheroma (blue) for both men (solid lines) and women (dashed lines).
A comparison of simulated individuals (a) without SCD and (b) with SCD demonstrates that for both men and women, the number of atheroma in those who suffer SCD are largely independent of age. (c) Box plots illustrating the difference in total number of atheroma in the simulated male (blue) and female (red) cohorts (box plot data includes minimum, 1st quartile, mean, 3rd quartile, maximum and relative number of patients represented as width). A clear distinction exists between the subpopulations of those simulated patients suffering from SCD and those who did not (the Welch's t-test, with T-statistics: 22.25 and 24.49; df: 992 and 833, for men and women, results in rejection of the null hypothesis with the p-value below 10−6).
