Table 2 Calculation of the sum of log-likelihood that the fraction of signal from mpDNA will follow a normal distribution of the positive controls vs. the negative controls.

From: Development of novel noninvasive prenatal testing protocol for whole autosomal recessive disease using picodroplet digital PCR

  

Positive control

Negative control

The first family

Paternal mutation

6.8677

-Infinity

Maternal mutation

−36.5065

−12.2726

The second family

Paternal mutation

−89.6183

-Infinity

The fourth family

Paternal mutation

−16.3308

−1050.1540

Maternal mutation

-Infinity

10.4021

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