This Article contains an error in the plot for Verapamil in Figure 5, where the red and black lines representing simulations of human ventricular action potentials under control conditions and in the presence of the drugs have been inverted. The correct Figure 5 appears below as Figure 1.
In addition, there are errors in the order of the legends of Figures 4, 5 and 6. The correct legends are:
Figure 4
Simulations of human Purkinje cell action potentials in control (red line) and in the putative presence of the drugs indicated above (black line). To calculate the conductances of ICaL, INa, IK1, IKS and IKR, the conductance block equation described in the Methods section was applied, using the concentrations and IC50 (or % of IK1 blockade) given in Fig. 1.
Figure 5
Simulations of human ventricular action potentials under control conditions (red line) and in the presence of the drugs indicated above (black line). To calculate the conductances of ICaL, INa, IK1, IKS and IKR, the conductance block equation (1) given in the Methods section was applied, using the concentrations and IC50 (or % of IK1 blockade) given in Fig. 1.
Figure 6
Simulations of ventricular action potentials in the presence of intracellular spermine (SPM) as shown above the graphs and using the GCaL given at left. Simulations were performed under control conditions (red line) and after 90% blockade of GKR.
Additional information
The online version of the original article can be found at 10.1038/srep37948
Rights and permissions
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
About this article
Cite this article
Le Guennec, JY., Thireau, J., Ouillé, A. et al. Correction: Corrigendum: Inter-individual variability and modeling of electrical activity: a possible new approach to explore cardiac safety?. Sci Rep 7, 42828 (2017). https://doi.org/10.1038/srep42828
Published:
DOI: https://doi.org/10.1038/srep42828