Bio-integrated microsystem technologies for Brain Computer Interface

High-performance microsystem technologies that can establish robust optical/electrical interfaces with implantable devices represent powerful tools   in neuroscience research and clinical utility of importance. Of particular interest  is biocompatible miniaturized design of integrated bioelectronics that offer sophisticated multi modal neuromodulation, including recording and stimulation of brain signals, and self-adaptive micro-/nano-engineering to the related brain tissues, at spatial scales from cellular resolution level to macroscopic area  coverage. Specifically, this special issue focus on the bioelectronic devices as stable implants, with form factors that provide mechanical compliance with conformal contact to the soft, curved, and time-dynamic neural systems. Such techniques can serve as neural interfaces that communicate seamlessly with living biology, offering great potential use for diagnosis and treatments of associated neurological disorders.