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Deep phenotyping can reveal how genetics, environment and stochasticity affect the development, physiology and behavior of an organism. In this Review, Dhaval S. Patel, Nan Xu and Hang Lu outline the technological and analytical developments that have enabled deep-phenotyping studies in Caenorhabditis elegans.
Treatment for bacterial sepsis remains limited beyond the use of antibiotics. Lingye Chen, Karen Welty-Wolf, and Bryan Kraft review nonhuman primate models of sepsis and highlight their advantages and limitations compared to other preclinical models.
