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Volume 14 Issue 7, July 2020

Chip-based super-resolution imaging

Depiction of chip-based structured illumination microscopy, where the evanescent field from an optical waveguide circuit excites fluorescence from cells grown on the chip’s surface. Multiple waveguide arms and thermo-optical phase modulators are used to generate an interference pattern that serves as the structured illumination.

See Helle et al.

Image: Balpreet S. Ahluwalia, UiT The Arctic University of Norway and Art by Dongwook Kim, Cube 3D Graphic. Cover Design: Bethany Vukomanovic

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  • Philip Warren Anderson is one of the founding fathers of modern condensed-matter physics. With his death on 29 March 2020, we have lost one of the most influential physicists of the twentieth century.

    • Diederik S. Wiersma
    • Bart A. van Tiggelen
    • Ad Lagendijk

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News & Views

  • Using a photonic chip to generate the patterns of light needed for structured illumination microscopy could reduce the cost and complexity of super-resolution imaging.

    • Sara Abrahamsson
    News & Views
  • A particular class of focused, pulsed light beams can propagate self-similarly in free space at a fixed group velocity. Now, scientists present a law of refraction that determines how the group velocity of these beams changes as they refract at an interface between two materials.

    • Vincent Ginis
    News & Views
  • Optical clocks held at slightly different heights provide a stringent test of general relativity comparable to space experiments and open new opportunities for clock-based geophysical sensing.

    • Kai Bongs
    • Yeshpal Singh
    News & Views
  • By utilizing exciton resonances in atomically thick semiconductors, researchers have now demonstrated the ultimate downscaling of optical lenses and reported on their efficacious electrical tunability.

    • Alex Krasnok
    News & Views
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Letters

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Articles

  • By harnessing the excitonic resonances of a monolayer of WS2 in the visible spectral range, large-area, actively tunable and atomically thin optical lenses can be realized.

    • Jorik van de Groep
    • Jung-Hwan Song
    • Mark L. Brongersma
    Article
  • The use of a photonic integrated circuit to both hold a biological sample and generate the necessary light patterns for structured illumination microscopy promises convenient super-resolution imaging.

    • Øystein Ivar Helle
    • Firehun Tsige Dullo
    • Balpreet Singh Ahluwalia
    Article
  • Transscleral optical phase imaging, which is based on transscleral flood illumination of the retina, is demonstrated to provide cellular-resolution, label-free, high-contrast images of the retinal layers over a large field of view without the drawback of a long exposure time.

    • Timothé Laforest
    • Mathieu Künzi
    • Christophe Moser
    Article
  • Robust terahertz wave transport is demonstrated on a silicon chip using the valley Hall topological phase. Error-free communication is achieved at a data rate of 11 Gbit s−1, enabling real-time transmission of uncompressed 4K high-definition video.

    • Yihao Yang
    • Yuichiro Yamagami
    • Ranjan Singh
    Article
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