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Following the landmark approval of imatinib 20 years ago, over 70 kinase inhibitors are now transforming the clinical care of multiple malignancies and a handful of other disorders.
The complement pathway plays key roles in host defence, but its excessive activation or dysregulation can lead to a variety of disorders. This poster overviews strategies to therapeutically intervene in the pathway and the new generation of complement inhibitors that are now in the clinic.
