Reviews & Analysis

This PrimeView highlights the epidemiology, pathophysiology, diagnosis, management and quality of life of patients with androgenetic alopecia, an inherited condition that causes hair loss.

In this Primer, Plikus and colleagues review the epidemiology, pathophysiology and diagnosis of androgenetic alopecia, an inherited hair loss condition that affects both men and women, and highlight the current and emerging treatment and management options.

This PrimeView highlights the diagnosis of Listeriosis and summarises its epidemiology, mechanisms and management. It accompanies the Primer on Listeriosis by Disson and colleagues.

Listeriosis is a food-borne bacterial infection that causes severe illness in at-risk populations. In this Primer, Disson et al. review the epidemiology and pathogenesis of the disease; discuss its diagnosis, prevention and management; and identify areas of research that need to be prioritized in the future.

This PrimeView highlights the mechanisms of lupus nephritis, and summarizes the epidemiology, diagnosis and management of this disease. It accompanies the Primer on this topic by Parodis et al.

Lupus nephritis is an autoimmune-mediated glomerulonephritis and a serious complication of systemic lupus erythematosus. In this Primer, Parodis and colleagues describe the epidemiology and pathophysiology of this disease, discuss current diagnosis and management, and highlight the effects on patient quality of life as well as future areas of research.

This PrimeView highlights the mechanisms of peripheral artery disease and summarises its epidemiology, diagnosis and management. It accompanies the Primer on peripheral artery disease by Aboyans and colleagues.

Peripheral artery disease is a vascular disorder characterized by narrowing of the peripheral arteries owing to atherosclerosis or thrombosis. In this Primer, Aboyans and colleagues review the epidemiology, pathophysiology, diagnosis and management of peripheral artery disease, and discuss areas for future research.

This PrimeView highlights the epidemiology, mechanisms, diagnosis, management and quality of life of patients with autoimmune encephalitis.

In this Primer, de Bruijin et al. discuss the epidemiology, pathophysiology, diagnosis, management and quality of life of adults with autoimmune encephalitis, a rare neurological condition that causes progressive inflammation of the brain. The authors also discuss unmet needs of the field and discuss strategies to improve long-term outcomes.

This PrimeView highlights the epidemiology, pathophysiology, diagnosis, management and quality of life of patients with diabetic retinal disease.

Diabetic retinal disease describes the spectrum of pathophysiological retinal changes due to diabetes mellitus. In this Primer, Sivaprasad et al. review the epidemiology, mechanisms, diagnosis and management of diabetic retinal disease, and highlight patient quality of life and future research areas.

This PrimeView highlights the epidemiology, mechanisms, diagnosis, management and the quality of life of patients with Lung metastases.

The lungs are a common metastatic site for several cancers, including colorectal cancer, primary lung cancer, breast cancer and prostate cancer. This Primer summarizes the epidemiology, mechanisms and diagnosis of lung metastasis, discusses the various treatment options and effects on quality of life, and highlights ongoing and future research areas.

This PrimeView highlights the mechanisms of hypertrophic cardiomyopathy and summarises its epidemiology, diagnosis and management. It accompanies the Primer on hypertrophic cardiomyopathy by Argirò and colleagues.

Hypertrophic cardiomyoapthy is a condition in which the left ventricle of the heart becomes thickened. In this Primer, Argirò and colleagues discuss the epidemiology, pathogenetic mechanisms, diagnosis and management of hypertrophic cardiomyoapthy and describe how the disease can affect patient quality of life.

This PrimeView highlights highlights the mechanisms of pleural mesothelioma, and summarizes the epidemiology, diagnosis, management of this disease. It accompanies the Primer on this topic by Fennell et al.

Pleural mesothelioma is a cancer that arises in the lining of the lung and is caused by exposure to asbestos. In this Primer, Fennell et al. discuss the epidemiology, pathophysiology, diagnosis and management of this disease, as well as patient quality of life and new research developments.

This PrimeView highlights the epidemiology, pathophysiology, diagnosis, management and quality of life of individuals with differences of sex development, a condition in which the development of chromosomal, gonadal, or anatomical sex is atypical.

Differences of sex development (DSD) encompass a group of rare congenital conditions characterized by atypical sex development. In this Primer, Flück and colleagues provide insights into our current understanding of rare DSD pathophysiology, its prevalence and diagnosis as well as challenges and controversies related to clinical management.