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Ten years ago, few people had heard of the term autophagy (literally 'self-eating'). But less than a decade later, research in the field has exploded, and recent studies have uncovered an integral role for autophagy in various human diseases.
SOS mutagenesis is the 'mutation-prone' cellular replication mechanism that is responsible for UV-induced mutations. More than 50 years of SOS mutagenesis research has exposed the underlying mechanisms of DNA-damage-induced mutagenesis that combine the overlapping functions of replication, repair and recombination.
